A Family Doctor’s Tale – OCCUPATIONAL ARSENIC POISONING
DOC WHAT IS OCCUPATIONAL ARSENIC POISONING?
Occupational Arsenic poisoning
An occupational Arsenic poisoning is a toxic metal poisoning condition caused by excessive exposure to Arsenic resulting in neurological, gastrointestinal and renal symptoms.
Arsenic poisoning occurs when workers are exposed to it due to accidents. Poisoning can occur when the arsenic is absorbed into the body by inhalation(organic) or skin contact(inorganic).
What are the Signs and symptoms of occupational Arsenic poisoning?
Acute Arsenic exposure at high levels can cause sudden onset of gastrointestinal and neurological symptoms such as nausea, vomiting,abdominal pain or dark urine.
The appearance of occupational Arsenic poisoning may be divided into inorganic and organic arsenic poisoning
Acute presentation of inorganic arsenic poisoning:
General:
1.dehydration
2.fever
3.anorexia
4.shock
GIT:
1.nausea
2.vomiting
3.diarrhea
4.abdominal pain
Neurological:
1.headache
2.delirium
3.vertigo
4.paresthesia
5.encephalopathy
Lungs:
breathlessness, bronchitis, cough
Blood:
acute hemolysis of red blood cells resulting in dark colored urine (termed black water urine)
Cardiovascular:
heart failure and arrhythmia
Long time exposure to inorganic arsenic may cause symptoms:
Skin changes:
1.discoloration -redness or darkening
2.swelling or hyperkeratosis (callus or corns)
3.whitish lines (Mee’s lines) in the finger nails
Neurological:
motor and sensory loss in nerves
Blood:
1.hemolysis of red blood cells
2.anemia
Liver:
liver enlargement and failure
Renal:
chronic nephritis and tubular degeneration
Acute presentation in organic arsenic or arsine poisoning:
General:
1.dehydration
2.chills
3.malaise
4.nausea
Cardiovascular:
1.abnormal heart condition and ECG.
Blood -Massive hemolysis of red blood cells with triad of
1.abdominal pain
2.bloody urine (Portwine urine)
3.jaundice
Diagnostic Criteria of Work relatedness:
A good occupational history of work exposure to arsenic is important in diagnosing work place arsenic poisoning.
Supporting workplace monitoring and reports will provide more evidence to determine the diagnosis of work related arsenic poisoning.
Investigation to establish work relationship to arsenic poisoning:
Get an occupational history to establish if the worker is exposed to inorganic arsenic during:
1.manufacture of pesticides, wood preservatives containing arsenic
2.manufacture and use of semiconductors in particular wafer
production and maintenance of ion implant machines)
3.manufacture of lead alloys, anti-fouling paints and pigments
4.Sawing, sanding and burning of wood treated with arsenical preservatives
5.manufacture and use of additives in animal and poultry feeds
6.Smelting of arsenic containing ores
Organic arsenic poisoning:
1.Manufacture of semiconductors (in particular wafer production and
maintenance of ion implant machines)
2.Accidental exposures during metal refining, waste treatment and
cleaning of tanks containing acid sludge
3.Smelting of arsenic containing metals
Get records of exposure monitoring from factories and companies to correlate with the worker’s test results such as:
a.patient’s periodical urine arsenic results
b.neurological and hematological examination
Management:
1.Treatment of all workers with abnormal urine and blood arsenic level results should be done and the blood tests repeated after every 3 months until results are normal
2.All workers with arsenic poisoning should be reassigned to another area without exposure to arsenic.
3.Some workers with severe signs of arsenic poisoning may required hospitalization.
4.maintain good personal hygiene , wear personal protective equipment and practice good work practices to prevent inhalation of toxic agent.
5.Avoid smoking and eating at workplaces which may be exposed to arsenic.
6.Put in place control measures to reduce exposure to arsenic
7.Education of workers of the dangers of arsenic poisoning and how to reduce exposure.
8.follow up on cases to monitor disease and whether the patient need hospitalization































































DOC I HAVE A PIN IN THE FOOT






























